Twin Pine Casino & Hotel is a Native American gaming resort in Middletown, California, owned by the Middletown Rancheria of Pomo Indians and operating since 1994. Located at 22223 Highway 29 in south Lake County near Napa Valley and Clear Lake, the 10,000 square foot casino features over 500 gaming machines and 12 table games including Blackjack, Poker, and Three Card Poker. The 60-room hotel includes luxury suites and deluxe accommodations, while Manzanita Restaurant provides fine dining and the smoke-free Grapevine Lounge hosts live entertainment with sports viewing and specialty drinks.